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Hedging against Antiviral Resistance during the Next Influenza Pandemic Using Small Stockpiles of an Alternative Chemotherapy
BACKGROUND: The effectiveness of single-drug antiviral interventions to reduce morbidity and mortality during the next influenza pandemic will be substantially weakened if transmissible strains emerge which are resistant to the stockpiled antiviral drugs. We developed a mathematical model to test th...
Autores principales: | Wu, Joseph T., Leung, Gabriel M., Lipsitch, Marc, Cooper, Ben S., Riley, Steven |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680070/ https://www.ncbi.nlm.nih.gov/pubmed/19440354 http://dx.doi.org/10.1371/journal.pmed.1000085 |
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