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A comparison on effects of normalisations in the detection of differentially expressed genes

BACKGROUND: Various normalisation techniques have been developed in the context of microarray analysis to try to correct expression measurements for experimental bias and random fluctuations. Major techniques include: total intensity normalisation; intensity dependent normalisation; and variance sta...

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Detalles Bibliográficos
Autores principales: Chiogna, Monica, Massa, Maria Sofia, Risso, Davide, Romualdi, Chiara
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680204/
https://www.ncbi.nlm.nih.gov/pubmed/19216778
http://dx.doi.org/10.1186/1471-2105-10-61