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A comparison on effects of normalisations in the detection of differentially expressed genes
BACKGROUND: Various normalisation techniques have been developed in the context of microarray analysis to try to correct expression measurements for experimental bias and random fluctuations. Major techniques include: total intensity normalisation; intensity dependent normalisation; and variance sta...
Autores principales: | Chiogna, Monica, Massa, Maria Sofia, Risso, Davide, Romualdi, Chiara |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680204/ https://www.ncbi.nlm.nih.gov/pubmed/19216778 http://dx.doi.org/10.1186/1471-2105-10-61 |
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