Novel Escherichia coli RF1 mutants with decreased translation termination activity and increased sensitivity to the cytotoxic effect of the bacterial toxins Kid and RelE

Novel mutations in prfA, the gene for the polypeptide release factor RF1 of Escherichia coli, were isolated using a positive genetic screen based on the parD (kis, kid) toxin–antitoxin system. This original approach allowed the direct selection of mutants with altered translational termination effic...

Descripción completa

Detalles Bibliográficos
Autores principales: Diago-Navarro, Elizabeth, Mora, Liliana, Buckingham, Richard H, Díaz-Orejas, Ramón, Lemonnier, Marc
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2008
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680264/
https://www.ncbi.nlm.nih.gov/pubmed/19019162
http://dx.doi.org/10.1111/j.1365-2958.2008.06510.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680264/
https://www.ncbi.nlm.nih.gov/pubmed/19019162
http://dx.doi.org/10.1111/j.1365-2958.2008.06510.x

Ejemplares similares