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Suppression of the MEK/ERK signaling pathway reverses depression-like behaviors of CRF(2)-deficient mice

The neuropeptide corticotropin-releasing factor (CRF) plays a critical role in the proper functioning of the stress response system through its actions on its receptors, CRF receptor 1 (CRF(1)) and CRF receptor 2 (CRF(2)), located at multiple anatomical sites. Clinical data indicate that stress resp...

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Detalles Bibliográficos
Autores principales: Todorovic, Cedomir, Sherrin, Tessi, Pitts, Matthew, Hippel, Cathrin, Rayner, Martin, Spiess, Joachim
Formato: Texto
Lenguaje:English
Publicado: 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680273/
https://www.ncbi.nlm.nih.gov/pubmed/18843268
http://dx.doi.org/10.1038/npp.2008.178