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Suppression of the MEK/ERK signaling pathway reverses depression-like behaviors of CRF(2)-deficient mice
The neuropeptide corticotropin-releasing factor (CRF) plays a critical role in the proper functioning of the stress response system through its actions on its receptors, CRF receptor 1 (CRF(1)) and CRF receptor 2 (CRF(2)), located at multiple anatomical sites. Clinical data indicate that stress resp...
Autores principales: | Todorovic, Cedomir, Sherrin, Tessi, Pitts, Matthew, Hippel, Cathrin, Rayner, Martin, Spiess, Joachim |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680273/ https://www.ncbi.nlm.nih.gov/pubmed/18843268 http://dx.doi.org/10.1038/npp.2008.178 |
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