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Disruption of d-alanyl esterification of Staphylococcus aureus cell wall teichoic acid by the β-lactam resistance modifier (−)-epicatechin gallate

OBJECTIVES: The naturally occurring polyphenol (−)-epicatechin gallate (ECg) increases oxacillin susceptibility in mecA-containing strains of Staphylococcus aureus. Decreased susceptibility to lysostaphin suggests alterations to the wall teichoic acid (WTA) content of ECg-grown bacteria. Changes in...

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Detalles Bibliográficos
Autores principales: Bernal, Patricia, Zloh, Mire, Taylor, Peter W.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680342/
https://www.ncbi.nlm.nih.gov/pubmed/19307172
http://dx.doi.org/10.1093/jac/dkp094