How do multi-stage, multi-arm trials compare to the traditional two-arm parallel group design – a reanalysis of 4 trials

BACKGROUND: To speed up the evaluation of new therapies, the multi-arm, multi-stage trial design was suggested previously by the authors. METHODS: In this paper, we evaluate the performance of the two-stage, multi-arm design using four cancer trials conducted at the MRC CTU. The performance of the d...

Descripción completa

Detalles Bibliográficos
Autores principales: Barthel, FM-S, Parmar, MKB, Royston, P
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680399/
https://www.ncbi.nlm.nih.gov/pubmed/19374739
http://dx.doi.org/10.1186/1745-6215-10-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680399/
https://www.ncbi.nlm.nih.gov/pubmed/19374739
http://dx.doi.org/10.1186/1745-6215-10-21

Ejemplares similares