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Characterization of the bovine type I IFN locus: rearrangements, expansions, and novel subfamilies

BACKGROUND: The Type I interferons (IFN) have major roles in the innate immune response to viruses, a function that is believed to have led to expansion in the number and complexity of their genes, although these genes have remained confined to single chromosomal region in all mammals so far examine...

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Detalles Bibliográficos
Autores principales: Walker, Angela M, Roberts, R Michael
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680415/
https://www.ncbi.nlm.nih.gov/pubmed/19393062
http://dx.doi.org/10.1186/1471-2164-10-187