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The Base Excision Repair System of Salmonella enterica serovar Typhimurium Counteracts DNA Damage by Host Nitric Oxide

Intracellular pathogens must withstand nitric oxide (NO·) generated by host phagocytes. Salmonella enterica serovar Typhimurium interferes with intracellular trafficking of inducible nitric oxide synthase (iNOS) and possesses multiple systems to detoxify NO·. Consequently, the level of NO· stress en...

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Detalles Bibliográficos
Autores principales: Richardson, Anthony R., Soliven, Khanh C., Castor, Margaret E., Barnes, Penelope D., Libby, Stephen J., Fang, Ferric C.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680585/
https://www.ncbi.nlm.nih.gov/pubmed/19478870
http://dx.doi.org/10.1371/journal.ppat.1000451