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Regional hippocampal differences in AKT survival signaling across the lifespan: Implications for CA1 vulnerability with aging

Distinct neuronal populations differ by the degree of damage caused from cellular stress. Hippocampal neurons of area CA1 are especially vulnerable to several stressors that increase with advanced age. We show here that survival signaling, as measured by activated AKT, was significantly reduced in t...

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Detalles Bibliográficos
Autores principales: Jackson, Travis C., Rani, Asha, Kumar, Ashok, Foster, Thomas C
Formato: Texto
Lenguaje:English
Publicado: 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680608/
https://www.ncbi.nlm.nih.gov/pubmed/19039330
http://dx.doi.org/10.1038/cdd.2008.171