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Identification of an Endogenous Ligand Bound to a Native Orphan Nuclear Receptor

Orphan nuclear receptors have been instrumental in identifying novel signaling pathways and therapeutic targets. However, identification of ligands for these receptors has often been based on random compound screens or other biased approaches. As a result, it remains unclear in many cases if the rep...

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Detalles Bibliográficos
Autores principales: Yuan, Xiaohui, Ta, Tuong Chi, Lin, Min, Evans, Jane R., Dong, Yinchen, Bolotin, Eugene, Sherman, Mark A., Forman, Barry M., Sladek, Frances M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680617/
https://www.ncbi.nlm.nih.gov/pubmed/19440305
http://dx.doi.org/10.1371/journal.pone.0005609