Functional Substitution by TAT-Utrophin in Dystrophin-Deficient Mice

BACKGROUND: The loss of dystrophin compromises muscle cell membrane stability and causes Duchenne muscular dystrophy and/or various forms of cardiomyopathy. Increased expression of the dystrophin homolog utrophin by gene delivery or pharmacologic up-regulation has been demonstrated to restore membra...

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Detalles Bibliográficos
Autores principales: Sonnemann, Kevin J., Heun-Johnson, Hanke, Turner, Amy J., Baltgalvis, Kristen A., Lowe, Dawn A., Ervasti, James M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680620/
https://www.ncbi.nlm.nih.gov/pubmed/19478831
http://dx.doi.org/10.1371/journal.pmed.1000083

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680620/
https://www.ncbi.nlm.nih.gov/pubmed/19478831
http://dx.doi.org/10.1371/journal.pmed.1000083

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