In Vitro Cytochrome P450 Formation of a Mono-Hydroxylated Metabolite of Zearalenone Exhibiting Estrogenic Activities: Possible Occurrence of This Metabolite in Vivo

The mycoestrogen zearalenone (ZEN), as well as its reduced metabolites, which belong to the endocrine disruptor bio-molecule family, are substrates for various enzymes involved in steroid metabolism. In addition to its reduction by the steroid dehydrogenase pathway, ZEN also interacts with hepatic d...

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Detalles Bibliográficos
Autores principales: Bravin, Frederique, Duca, Radu C., Balaguer, Patrick, Delaforge, Marcel
Formato: Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680649/
https://www.ncbi.nlm.nih.gov/pubmed/19468341
http://dx.doi.org/10.3390/ijms10041824

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680649/
https://www.ncbi.nlm.nih.gov/pubmed/19468341
http://dx.doi.org/10.3390/ijms10041824

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