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DNA polymerase switching: effects on spontaneous mutagenesis in Escherichia coli

Escherichia coli possesses five known DNA polymerases (pols). Pol III holoenzyme is the cell's main replicase, while pol I is responsible for the maturation of Okazaki fragments and filling gaps generated during nucleotide excision repair. Pols II, IV and V are significantly upregulated as part...

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Detalles Bibliográficos
Autores principales: Curti, Elena, McDonald, John P, Mead, Samantha, Woodgate, Roger
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680738/
https://www.ncbi.nlm.nih.gov/pubmed/19019142
http://dx.doi.org/10.1111/j.1365-2958.2008.06526.x