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DNA polymerase switching: effects on spontaneous mutagenesis in Escherichia coli
Escherichia coli possesses five known DNA polymerases (pols). Pol III holoenzyme is the cell's main replicase, while pol I is responsible for the maturation of Okazaki fragments and filling gaps generated during nucleotide excision repair. Pols II, IV and V are significantly upregulated as part...
Autores principales: | Curti, Elena, McDonald, John P, Mead, Samantha, Woodgate, Roger |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680738/ https://www.ncbi.nlm.nih.gov/pubmed/19019142 http://dx.doi.org/10.1111/j.1365-2958.2008.06526.x |
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