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Antidepressants inhibit P2X(4 )receptor function: a possible involvement in neuropathic pain relief

BACKGROUND: Neuropathic pain is characterized by pain hypersensitivity to innocuous stimuli (tactile allodynia) that is nearly always resistant to known treatments such as non-steroidal anti-inflammatory drugs or even opioids. It has been reported that some antidepressants are effective for treating...

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Detalles Bibliográficos
Autores principales: Nagata, Kenichiro, Imai, Toshiyasu, Yamashita, Tomohiro, Tsuda, Makoto, Tozaki-Saitoh, Hidetoshi, Inoue, Kazuhide
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680826/
https://www.ncbi.nlm.nih.gov/pubmed/19389225
http://dx.doi.org/10.1186/1744-8069-5-20