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Exploring the functional interaction between POSH and ALIX and the relevance to HIV-1 release

BACKGROUND: The ALG2-interacting protein X (ALIX)/AIP1 is an adaptor protein with multiple functions in intracellular protein trafficking that plays a central role in the biogenesis of enveloped viruses. The ubiquitin E3-ligase POSH (plenty of SH3) augments HIV-1 egress by facilitating the transport...

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Detalles Bibliográficos
Autores principales: Votteler, Jörg, Iavnilovitch, Elena, Fingrut, Orit, Shemesh, Vivian, Taglicht, Daniel, Erez, Omri, Sörgel, Stefan, Walther, Torsten, Bannert, Norbert, Schubert, Ulrich, Reiss, Yuval
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680910/
https://www.ncbi.nlm.nih.gov/pubmed/19393081
http://dx.doi.org/10.1186/1471-2091-10-12