Full Factorial Analysis of Mammalian and Avian Influenza Polymerase Subunits Suggests a Role of an Efficient Polymerase for Virus Adaptation

Amongst all the internal gene segments (PB2. PB1, PA, NP, M and NS), the avian PB1 segment is the only one which was reassorted into the human H2N2 and H3N2 pandemic strains. This suggests that the reassortment of polymerase subunit genes between mammalian and avian influenza viruses might play role...

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Detalles Bibliográficos
Autores principales: Li, Olive T. W., Chan, Michael C. W., Leung, Cynthia S. W., Chan, Renee W. Y., Guan, Yi, Nicholls, John M., Poon, Leo L. M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680953/
https://www.ncbi.nlm.nih.gov/pubmed/19462010
http://dx.doi.org/10.1371/journal.pone.0005658

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680953/
https://www.ncbi.nlm.nih.gov/pubmed/19462010
http://dx.doi.org/10.1371/journal.pone.0005658

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