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Single-Molecule LATE-PCR Analysis of Human Mitochondrial Genomic Sequence Variations

It is thought that changes in mitochondrial DNA are associated with many degenerative diseases, including Alzheimer's and diabetes. Much of the evidence, however, depends on correlating disease states with changing levels of heteroplasmy within populations of mitochondrial genomes, rather than...

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Detalles Bibliográficos
Autores principales: Osborne, Adam, Reis, Arthur H., Bach, Loren, Wangh, Lawrence J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680954/
https://www.ncbi.nlm.nih.gov/pubmed/19461959
http://dx.doi.org/10.1371/journal.pone.0005636