Homologous desensitization of signalling by the alpha (α) isoform of the human thromboxane A(2) receptor: A specific role for nitric oxide signalling

Thromboxane (TX) A(2) plays a central role in hemostasis, regulating platelet activation status and vascular tone. We have recently established that the TPβ isoform of the human TXA(2) receptor (TP) undergoes rapid, agonist-induced homologous desensitization of signalling largely through a G protein...

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Detalles Bibliográficos
Autores principales: Kelley-Hickie, Leanne P., O'Keeffe, Martina B., Reid, Helen M., Kinsella, B. Therese
Formato: Texto
Lenguaje:English
Publicado: Elsevier Pub. Co 2007
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680961/
https://www.ncbi.nlm.nih.gov/pubmed/17466390
http://dx.doi.org/10.1016/j.bbamcr.2007.03.012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680961/
https://www.ncbi.nlm.nih.gov/pubmed/17466390
http://dx.doi.org/10.1016/j.bbamcr.2007.03.012

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