Agonist-dependent internalization and trafficking of the human prostacyclin receptor: A direct role for Rab5a GTPase

The human prostacyclin receptor (hIP) undergoes rapid agonist-induced internalization by largely unknown mechanism(s). Herein the involvement of Rab5 in regulating cicaprost-induced internalization of the hIP expressed in human embryonic kidney 293 cells was investigated. Over-expression of Rab5a si...

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Detalles Bibliográficos
Autores principales: O'Keeffe, Martina B., Reid, Helen M., Kinsella, B. Therese
Formato: Texto
Lenguaje:English
Publicado: Elsevier Pub. Co 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680976/
https://www.ncbi.nlm.nih.gov/pubmed/18498773
http://dx.doi.org/10.1016/j.bbamcr.2008.04.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680976/
https://www.ncbi.nlm.nih.gov/pubmed/18498773
http://dx.doi.org/10.1016/j.bbamcr.2008.04.010

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