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Agonist-dependent internalization and trafficking of the human prostacyclin receptor: A direct role for Rab5a GTPase
The human prostacyclin receptor (hIP) undergoes rapid agonist-induced internalization by largely unknown mechanism(s). Herein the involvement of Rab5 in regulating cicaprost-induced internalization of the hIP expressed in human embryonic kidney 293 cells was investigated. Over-expression of Rab5a si...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Pub. Co
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680976/ https://www.ncbi.nlm.nih.gov/pubmed/18498773 http://dx.doi.org/10.1016/j.bbamcr.2008.04.010 |