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Species and Strain Glycosylation Patterns of PrP(Sc)

BACKGROUND: A key event in transmissible spongiform encephalopathies (TSEs) is the conversion of the soluble, protease-sensitive glycosylated prion protein (PrP(C)) to an abnormally structured, aggregated and partially protease-resistant isoform (PrP(Sc)). Both PrP isoforms bear two potential glycos...

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Detalles Bibliográficos
Autores principales: Xanthopoulos, Konstantinos, Polymenidou, Magdalini, Bellworthy, Sue J., Benestad, Sylvie L., Sklaviadis, Theodoros
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680983/
https://www.ncbi.nlm.nih.gov/pubmed/19461968
http://dx.doi.org/10.1371/journal.pone.0005633