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Species and Strain Glycosylation Patterns of PrP(Sc)
BACKGROUND: A key event in transmissible spongiform encephalopathies (TSEs) is the conversion of the soluble, protease-sensitive glycosylated prion protein (PrP(C)) to an abnormally structured, aggregated and partially protease-resistant isoform (PrP(Sc)). Both PrP isoforms bear two potential glycos...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680983/ https://www.ncbi.nlm.nih.gov/pubmed/19461968 http://dx.doi.org/10.1371/journal.pone.0005633 |