HIV-1 RNA Dysregulates the Natural TLR Response to Subclinical Endotoxemia in Kenyan Female Sex-Workers

BACKGROUND: Subclinical endotoxemia has been reported in HIV-1 infected persons and may drive systemic immune activation and pathogenesis. Proinflammatory responsiveness to endotoxin (LPS) is mediated by Toll-like receptor 4 (TLR4). We therefore examined the association between plasma LPS levels, HI...

Descripción completa

Detalles Bibliográficos
Autores principales: Lester, Richard T., Yao, Xiao-Dan, Ball, T. Blake, McKinnon, Lyle R., Omange, Were R., Kaul, Rupert, Wachihi, Charles, Jaoko, Walter, Rosenthal, Kenneth L., Plummer, Francis A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680984/
https://www.ncbi.nlm.nih.gov/pubmed/19461969
http://dx.doi.org/10.1371/journal.pone.0005644

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680984/
https://www.ncbi.nlm.nih.gov/pubmed/19461969
http://dx.doi.org/10.1371/journal.pone.0005644

Ejemplares similares