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Redefining the Scl-70 indirect immunofluorescence pattern: autoantibodies to DNA topoisomerase I yield a specific compound immunofluorescence pattern

Objectives. To report on a novel IIF pattern specifically associated with antibodies to DNA topo I. Methods. A novel compound IF pattern, designated Scl-70 pattern, was characterized in routine ANA-HEp-2 IIF screening. Within the last 3 years, all serum samples presenting the Scl-70 pattern at the A...

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Detalles Bibliográficos
Autores principales: Dellavance, Alessandra, Gallindo, Cristiane, Soares, Mariana Guanaes, da Silva, Neusa Pereira, Mortara, Renato Arruda, Andrade, Luís Eduardo Coelho
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2681287/
https://www.ncbi.nlm.nih.gov/pubmed/19395540
http://dx.doi.org/10.1093/rheumatology/kep070