BH3 Peptides Induce Mitochondrial Fission and Cell Death Independent of BAX/BAK

BH3 only proteins trigger cell death by interacting with pro- and anti-apoptotic members of the BCL-2 family of proteins. Here we report that BH3 peptides corresponding to the death domain of BH3-only proteins, which bind all the pro-survival BCL-2 family proteins, induce cell death in the absence o...

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Detalles Bibliográficos
Autores principales: Shroff, Emelyn H., Snyder, Colleen M., Budinger, G. R. Scott, Jain, Manu, Chew, Teng-Leong, Khuon, Satya, Perlman, Harris, Chandel, Navdeep S.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2681411/
https://www.ncbi.nlm.nih.gov/pubmed/19468307
http://dx.doi.org/10.1371/journal.pone.0005646

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2681411/
https://www.ncbi.nlm.nih.gov/pubmed/19468307
http://dx.doi.org/10.1371/journal.pone.0005646

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