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Macrophage CD74 contributes to MIF-induced pulmonary inflammation

BACKGROUND: MIF is a critical mediator of the host defense, and is involved in both acute and chronic responses in the lung. Neutralization of MIF reduces neutrophil accumulation into the lung in animal models. We hypothesized that MIF, in the alveolar space, promotes neutrophil accumulation via act...

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Detalles Bibliográficos
Autores principales: Takahashi, Koichiro, Koga, Kiyokazu, Linge, Helena M, Zhang, Yinzhong, Lin, Xinchun, Metz, Christine N, Al-Abed, Yousef, Ojamaa, Kaie, Miller, Edmund J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2681459/
https://www.ncbi.nlm.nih.gov/pubmed/19413900
http://dx.doi.org/10.1186/1465-9921-10-33