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Proteins of the origin recognition complex (ORC) and DNA topoisomerases on mammalian chromatin

BACKGROUND: The process of DNA replication requires the separation of complementary DNA strands. In this process, the unwinding of circularly closed or long DNA duplices leads to torsional tensions which must be released by topoisomerases. So topoisomerases play an important role in DNA replication....

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Detalles Bibliográficos
Autores principales: Hu, Hong-gang, Baack, Martina, Knippers, Rolf
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2681468/
https://www.ncbi.nlm.nih.gov/pubmed/19397829
http://dx.doi.org/10.1186/1471-2199-10-36