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Proteins of the origin recognition complex (ORC) and DNA topoisomerases on mammalian chromatin
BACKGROUND: The process of DNA replication requires the separation of complementary DNA strands. In this process, the unwinding of circularly closed or long DNA duplices leads to torsional tensions which must be released by topoisomerases. So topoisomerases play an important role in DNA replication....
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2681468/ https://www.ncbi.nlm.nih.gov/pubmed/19397829 http://dx.doi.org/10.1186/1471-2199-10-36 |