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Purification of polyclonal anti-conformational antibodies for use in affinity selection from random peptide phage display libraries: A study using the hydatid vaccine EG95

The use of polyclonal antibodies to screen random peptide phage display libraries often results in the recognition of a large number of peptides that mimic linear epitopes on various proteins. There appears to be a bias in the use of this technology toward the selection of peptides that mimic linear...

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Detalles Bibliográficos
Autores principales: Read, A.J., Gauci, C.G., Lightowlers, M.W.
Formato: Texto
Lenguaje:English
Publicado: Elsevier 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2682179/
https://www.ncbi.nlm.nih.gov/pubmed/19349218
http://dx.doi.org/10.1016/j.jchromb.2009.03.036