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Structural Adaptation and Heterogeneity of Normal and Tumor Microvascular Networks
Relative to normal tissues, tumor microcirculation exhibits high structural and functional heterogeneity leading to hypoxic regions and impairing treatment efficacy. Here, computational simulations of blood vessel structural adaptation are used to explore the hypothesis that abnormal adaptive respon...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2682204/ https://www.ncbi.nlm.nih.gov/pubmed/19478883 http://dx.doi.org/10.1371/journal.pcbi.1000394 |