Structural Adaptation and Heterogeneity of Normal and Tumor Microvascular Networks

Relative to normal tissues, tumor microcirculation exhibits high structural and functional heterogeneity leading to hypoxic regions and impairing treatment efficacy. Here, computational simulations of blood vessel structural adaptation are used to explore the hypothesis that abnormal adaptive respon...

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Detalles Bibliográficos
Autores principales: Pries, Axel R., Cornelissen, Annemiek J. M., Sloot, Anoek A., Hinkeldey, Marlene, Dreher, Matthew R., Höpfner, Michael, Dewhirst, Mark W., Secomb, Timothy W.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2682204/
https://www.ncbi.nlm.nih.gov/pubmed/19478883
http://dx.doi.org/10.1371/journal.pcbi.1000394

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