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Exploring causality via identification of SNPs or haplotypes responsible for a linkage signal
In a small chromosomal region, a number of polymorphisms may be both linked to and associated with a disease. Distinguishing the potential causal sites from those indirectly associated due to linkage disequilibrium (LD) with a causal site is an important problem. This problem may be approached by de...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Wiley Subscription Services, Inc., A Wiley Company
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2682330/ https://www.ncbi.nlm.nih.gov/pubmed/17508343 http://dx.doi.org/10.1002/gepi.20236 |