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Exploring causality via identification of SNPs or haplotypes responsible for a linkage signal

In a small chromosomal region, a number of polymorphisms may be both linked to and associated with a disease. Distinguishing the potential causal sites from those indirectly associated due to linkage disequilibrium (LD) with a causal site is an important problem. This problem may be approached by de...

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Detalles Bibliográficos
Autores principales: Biernacka, Joanna M, Cordell, Heather J
Formato: Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2682330/
https://www.ncbi.nlm.nih.gov/pubmed/17508343
http://dx.doi.org/10.1002/gepi.20236

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