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Developing a novel rabbit model of atherosclerotic plaque rupture and thrombosis by cold-induced endothelial injury

BACKGROUND: It is widely believed that atherosclerotic plaque rupture and subsequent thrombosis leads to acute coronary events and stroke. However, study of the mechanism and treatment of human plaque rupture is hampered by lack of a suitable animal model. Our aim was to develop a novel animal model...

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Detalles Bibliográficos
Autores principales: Fang, Shun-Miao, Zhang, Qing-Hua, Jiang, Zhi-Xin
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2682487/
https://www.ncbi.nlm.nih.gov/pubmed/19344521
http://dx.doi.org/10.1186/1423-0127-16-39