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Developing a novel rabbit model of atherosclerotic plaque rupture and thrombosis by cold-induced endothelial injury
BACKGROUND: It is widely believed that atherosclerotic plaque rupture and subsequent thrombosis leads to acute coronary events and stroke. However, study of the mechanism and treatment of human plaque rupture is hampered by lack of a suitable animal model. Our aim was to develop a novel animal model...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2682487/ https://www.ncbi.nlm.nih.gov/pubmed/19344521 http://dx.doi.org/10.1186/1423-0127-16-39 |