Small Interfering RNA Targeting M2 Gene Induces Effective and Long Term Inhibition of Influenza A Virus Replication

RNA interference (RNAi) provides a powerful new means to inhibit viral infection specifically. However, the selection of siRNA-resistant viruses is a major concern in the use of RNAi as antiviral therapeutics. In this study, we conducted a lentiviral vector with a H1-short hairpin RNA (shRNA) expres...

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Detalles Bibliográficos
Autores principales: Sui, Hong-Yan, Zhao, Guang-Yu, Huang, Jian-Dong, Jin, Dong-Yan, Yuen, Kwok-Yung, Zheng, Bo-Jian
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2682565/
https://www.ncbi.nlm.nih.gov/pubmed/19479060
http://dx.doi.org/10.1371/journal.pone.0005671

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2682565/
https://www.ncbi.nlm.nih.gov/pubmed/19479060
http://dx.doi.org/10.1371/journal.pone.0005671

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