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Phase I Metabolic Genes and Risk of Lung Cancer: Multiple Polymorphisms and mRNA Expression

Polymorphisms in genes coding for enzymes that activate tobacco lung carcinogens may generate inter-individual differences in lung cancer risk. Previous studies had limited sample sizes, poor exposure characterization, and a few single nucleotide polymorphisms (SNPs) tested in candidate genes. We an...

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Detalles Bibliográficos
Autores principales: Rotunno, Melissa, Yu, Kai, Lubin, Jay H., Consonni, Dario, Pesatori, Angela C., Goldstein, Alisa M., Goldin, Lynn R., Wacholder, Sholom, Welch, Robert, Burdette, Laurie, Chanock, Stephen J., Bertazzi, Pier Alberto, Tucker, Margaret A., Caporaso, Neil E., Chatterjee, Nilanjan, Bergen, Andrew W., Landi, Maria Teresa
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2682568/
https://www.ncbi.nlm.nih.gov/pubmed/19479063
http://dx.doi.org/10.1371/journal.pone.0005652