A Novel Two Mode-Acting Inhibitor of ABCG2-Mediated Multidrug Transport and Resistance in Cancer Chemotherapy

BACKGROUND: Multidrug resistance (MDR) is a major problem in successful treatment of cancers. Human ABCG2, a member of the ATP-binding cassette transporter superfamily, plays a key role in MDR and an important role in protecting cancer stem cells. Knockout of ABCG2 had no apparent adverse effect on...

Descripción completa

Detalles Bibliográficos
Autores principales: Peng, Hui, Dong, Zizheng, Qi, Jing, Yang, Youyun, Liu, Yang, Li, Zhaomin, Xu, Junkang, Zhang, Jian-Ting
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2682573/
https://www.ncbi.nlm.nih.gov/pubmed/19479068
http://dx.doi.org/10.1371/journal.pone.0005676

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2682573/
https://www.ncbi.nlm.nih.gov/pubmed/19479068
http://dx.doi.org/10.1371/journal.pone.0005676

Ejemplares similares