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A Novel Two Mode-Acting Inhibitor of ABCG2-Mediated Multidrug Transport and Resistance in Cancer Chemotherapy

BACKGROUND: Multidrug resistance (MDR) is a major problem in successful treatment of cancers. Human ABCG2, a member of the ATP-binding cassette transporter superfamily, plays a key role in MDR and an important role in protecting cancer stem cells. Knockout of ABCG2 had no apparent adverse effect on...

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Detalles Bibliográficos
Autores principales:	Peng, Hui, Dong, Zizheng, Qi, Jing, Yang, Youyun, Liu, Yang, Li, Zhaomin, Xu, Junkang, Zhang, Jian-Ting
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2682573/ https://www.ncbi.nlm.nih.gov/pubmed/19479068 http://dx.doi.org/10.1371/journal.pone.0005676

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