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Impact of Growth Hormone (GH) Deficiency and GH Replacement upon Thymus Function in Adult Patients
BACKGROUND: Despite age-related adipose involution, T cell generation in the thymus (thymopoiesis) is maintained beyond puberty in adults. In rodents, growth hormone (GH), insulin-like growth factor-1 (IGF-1), and GH secretagogues reverse age-related changes in thymus cytoarchitecture and increase t...
Autores principales: | , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2682582/ https://www.ncbi.nlm.nih.gov/pubmed/19479077 http://dx.doi.org/10.1371/journal.pone.0005668 |