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Sox17 Promotes Cell Cycle Progression and Inhibits TGF-β/Smad3 Signaling to Initiate Progenitor Cell Behavior in the Respiratory Epithelium

The Sry-related high mobility group box transcription factor Sox17 is required for diverse developmental processes including endoderm formation, vascular development, and fetal hematopoietic stem cell maintenance. Expression of Sox17 in mature respiratory epithelial cells causes proliferation and li...

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Detalles Bibliográficos
Autores principales: Lange, Alexander W., Keiser, Angela R., Wells, James M., Zorn, Aaron M., Whitsett, Jeffrey A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2682659/
https://www.ncbi.nlm.nih.gov/pubmed/19479035
http://dx.doi.org/10.1371/journal.pone.0005711