c-Jun NH(2)-Terminal Kinase Activity in Subcutaneous Adipose Tissue but Not Nuclear Factor-κB Activity in Peripheral Blood Mononuclear Cells Is an Independent Determinant of Insulin Resistance in Healthy Individuals

OBJECTIVE: Chronic low-grade activation of the immune system (CLAIS) predicts type 2 diabetes via a decrease in insulin sensitivity. Our study investigated potential relationships between nuclear factor-κB (NF-κB) and c-Jun NH(2)-terminal kinase (JNK) pathways—two pathways proposed as the link betwe...

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Detalles Bibliográficos
Autores principales: Sourris, Karly C., Lyons, Jasmine G., de Courten, Maximilian P.J., Dougherty, Sonia L., Henstridge, Darren C., Cooper, Mark E., Hage, Michelle, Dart, Anthony, Kingwell, Bronwyn A., Forbes, Josephine M., de Courten, Barbora
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2682665/
https://www.ncbi.nlm.nih.gov/pubmed/19258436
http://dx.doi.org/10.2337/db08-1725

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2682665/
https://www.ncbi.nlm.nih.gov/pubmed/19258436
http://dx.doi.org/10.2337/db08-1725

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