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Type 2 Diabetes Risk Alleles Are Associated With Reduced Size at Birth

OBJECTIVE: Low birth weight is associated with an increased risk of type 2 diabetes. The mechanisms underlying this association are unknown and may represent intrauterine programming or two phenotypes of one genotype. The fetal insulin hypothesis proposes that common genetic variants that reduce ins...

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Detalles Bibliográficos
Autores principales: Freathy, Rachel M., Bennett, Amanda J., Ring, Susan M., Shields, Beverley, Groves, Christopher J., Timpson, Nicholas J., Weedon, Michael N., Zeggini, Eleftheria, Lindgren, Cecilia M., Lango, Hana, Perry, John R.B., Pouta, Anneli, Ruokonen, Aimo, Hyppönen, Elina, Power, Chris, Elliott, Paul, Strachan, David P., Järvelin, Marjo-Riitta, Smith, George Davey, McCarthy, Mark I., Frayling, Timothy M., Hattersley, Andrew T.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2682672/
https://www.ncbi.nlm.nih.gov/pubmed/19228808
http://dx.doi.org/10.2337/db08-1739