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Type 2 Diabetes Risk Alleles Are Associated With Reduced Size at Birth
OBJECTIVE: Low birth weight is associated with an increased risk of type 2 diabetes. The mechanisms underlying this association are unknown and may represent intrauterine programming or two phenotypes of one genotype. The fetal insulin hypothesis proposes that common genetic variants that reduce ins...
Autores principales: | Freathy, Rachel M., Bennett, Amanda J., Ring, Susan M., Shields, Beverley, Groves, Christopher J., Timpson, Nicholas J., Weedon, Michael N., Zeggini, Eleftheria, Lindgren, Cecilia M., Lango, Hana, Perry, John R.B., Pouta, Anneli, Ruokonen, Aimo, Hyppönen, Elina, Power, Chris, Elliott, Paul, Strachan, David P., Järvelin, Marjo-Riitta, Smith, George Davey, McCarthy, Mark I., Frayling, Timothy M., Hattersley, Andrew T. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2682672/ https://www.ncbi.nlm.nih.gov/pubmed/19228808 http://dx.doi.org/10.2337/db08-1739 |
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