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Diabetic Retinal Neurodegeneration Is Associated With Mitochondrial Oxidative Stress and Is Improved by an Angiotensin Receptor Blocker in a Model Combining Hypertension and Diabetes

OBJECTIVE: Diabetic retinopathy displays the features of a neurodegenerative disease. Oxidative stress is involved in the pathogenesis of diabetic retinopathy. This investigation sought to determine whether hypertension exacerbates the oxidative stress, neurodegeneration, and mitochondrial dysfuncti...

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Detalles Bibliográficos
Autores principales: Silva, Kamila C., Rosales, Mariana A.B., Biswas, Subrata K., Lopes de Faria, Jose B., Lopes de Faria, Jacqueline M.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2682683/
https://www.ncbi.nlm.nih.gov/pubmed/19289456
http://dx.doi.org/10.2337/db09-0166