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Diabetic Retinal Neurodegeneration Is Associated With Mitochondrial Oxidative Stress and Is Improved by an Angiotensin Receptor Blocker in a Model Combining Hypertension and Diabetes
OBJECTIVE: Diabetic retinopathy displays the features of a neurodegenerative disease. Oxidative stress is involved in the pathogenesis of diabetic retinopathy. This investigation sought to determine whether hypertension exacerbates the oxidative stress, neurodegeneration, and mitochondrial dysfuncti...
Autores principales: | Silva, Kamila C., Rosales, Mariana A.B., Biswas, Subrata K., Lopes de Faria, Jose B., Lopes de Faria, Jacqueline M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2682683/ https://www.ncbi.nlm.nih.gov/pubmed/19289456 http://dx.doi.org/10.2337/db09-0166 |
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