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Development of Selective Axonopathy in Adult Sensory Neurons Isolated From Diabetic Rats: Role of Glucose-Induced Oxidative Stress

OBJECTIVE: Reactive oxygen species (ROS) are pro-oxidant factors in distal neurodegeneration in diabetes. We tested the hypothesis that sensory neurons exposed to type 1 diabetes would exhibit enhanced ROS and oxidative stress and determined whether this stress was associated with abnormal axon outg...

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Detalles Bibliográficos
Autores principales: Zherebitskaya, Elena, Akude, Eli, Smith, Darrell R., Fernyhough, Paul
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2682687/
https://www.ncbi.nlm.nih.gov/pubmed/19252136
http://dx.doi.org/10.2337/db09-0034