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Development of Selective Axonopathy in Adult Sensory Neurons Isolated From Diabetic Rats: Role of Glucose-Induced Oxidative Stress
OBJECTIVE: Reactive oxygen species (ROS) are pro-oxidant factors in distal neurodegeneration in diabetes. We tested the hypothesis that sensory neurons exposed to type 1 diabetes would exhibit enhanced ROS and oxidative stress and determined whether this stress was associated with abnormal axon outg...
Autores principales: | Zherebitskaya, Elena, Akude, Eli, Smith, Darrell R., Fernyhough, Paul |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2682687/ https://www.ncbi.nlm.nih.gov/pubmed/19252136 http://dx.doi.org/10.2337/db09-0034 |
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