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Systemic Inhibition of NF-κB Activation Protects from Silicosis

BACKGROUND: Silicosis is a complex lung disease for which no successful treatment is available and therefore lung transplantation is a potential alternative. Tumor necrosis factor alpha (TNFα) plays a central role in the pathogenesis of silicosis. TNFα signaling is mediated by the transcription fact...

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Detalles Bibliográficos
Autores principales: Di Giuseppe, Michelangelo, Gambelli, Federica, Hoyle, Gary W., Lungarella, Giuseppe, Studer, Sean M., Richards, Thomas, Yousem, Sam, McCurry, Ken, Dauber, James, Kaminski, Naftali, Leikauf, George, Ortiz, Luis A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2682759/
https://www.ncbi.nlm.nih.gov/pubmed/19479048
http://dx.doi.org/10.1371/journal.pone.0005689